We focus on cellular to systemic health, not just on symptoms

Providing ionic calcium in supplement form can help aging cells to restore proper communications to bring in amazing self-healing

Bringing Unique Technology

Using our breakthrough SAC technology that increases the bioavailability of ionic calcium of calcium carbonate, Pronuvia helps people to regain calcium homeostasis to boost cellular to systemic health.

Our Commitments

Pronuvia is dedicated to improving the lives of patients with ongoing clinical research.   Pronuvia’s approach begins by utilizing the human body’s natural potential to achieve optimal health by restoring our body’s intricate calcium balance which regulates calcium signaling. Sigma Anti-bonding Calcium (SAC) which delivers more ionic calcium effectively takes care of the age-related ionic calcium deficiency and pulls our system back into the proper balance.

Pronuvia has supported the health of over

10,000 people

that have voluntarily participated in our clinical research projects through participating physicians.

Bringing affordable, supplement-based optimal healthcare to everybody is the grand ambition of Pronuvia.

Research Team in association with CBHI (Calcium & Bone Health Institute, Canada)

  • Paul K. Lee (Chemistry, Ph.D) – inventor of SAC
  • Martin Chun (Material, Ph.D)
  • O.S. Lee (Foods Science, Ph.D)
  • Edward Lee (Materials Eng. Ph.D)
  • James Lee (Toxicology, Ph.D)
  • W.S. Kim (Material, Ph.D)
  • Chris Choe (Energy, Ph.D)


Our lab in Canada received the endorsement as a natural health product exporter, featured on 2016 & 2017 British Columbia Agrifood and Seafood Export-Ready Business Catalogue.

Collaborative Research

The experts of multiple myeloma cancer research in the UAMS Rockefeller Cancer Institute are partnering with CBHI in studying and finding the promising effects of SAC in future treatments for this debilitating disease.  The research is currently ongoing as of 2020.

Multiple myeloma (MM) is the second most common hematological malignancy. It mostly occurs at older ages and remains an incurable disease. MM is a B cell cancer mainly characterized by the proliferation of malignant plasma cells in the bone marrow, the presence of monoclonal serum immunoglobulin, and the occurrence of osteolytic lesions.  Bone remodeling effects of SAC by increasing the bone turnover rate through stimulation of osteoclast and osteoblast activity place SAC as a good candidate for novel myeloma therapy.

Our Research Partners in Collaboration with CBHI

SAC provides enough calcium ion directly into our system to trigger a cascade of natural health optimization.

Slight elevation of calcium ion concentration in our body do wonders following the natural pathways inherent in our system.*

Sigma Anti-bonding Calcium
(SAC - CaCO3)

The result of 10 years of intense research and development

SAC (Sigma Antibonding Calcium) is the world’s true first calcium-ion delivery system which safely and effectively elevates the threshold level of calcium-ion concentration in our blood (0.1mg/dL) to initiate a cascade of hormonal responses that helps awaken our body’s optimal health!*

SAC Major Benefits

SAC as
Calcium Navigator

  • Navigates calcium to where it is needed most– our bones.
  • Restores calcium homeostasis to balance calcium throughout our body*

SAC as Calcium

  • Stimulates the secretion of thyroid hormone (calcitonin)
  • Activates inactive calcium for use by the body.*

SAC as Hormone

  • Assures that calcium will directly reach the bone and will not be deposited in the kidneys and blood vessels.*
  • Helps clean up problematic calcium deposits

SAC as Bones
Mineral Rebuilder

  • Adequate SAC intake, as part of a healthful diet, along with physical activity, may reduce the risk of osteoporosis in life

Learn more about Pronuvia and the groundbreaking SAC technology today!

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