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Diabetes

NF-κB, inflammation and metabolic disease

By | Cardiovascular, Diabetes, Inflammation

NF-κB, inflammation and metabolic disease

Rebecca G. Baker, Matthew S. Hayden, and Sankar Ghosh*
Department of Microbiology & Immunology, College of Physicians and Surgeons, Columbia
University, New York, NY 10032

Metabolic disorders including obesity, type 2 diabetes and atherosclerosis have been viewed historically as lipid storage disorders brought about by overnutrition. It is now widely appreciated that chronic low-grade inflammation plays a key role in the initiation, propagation and development of metabolic diseases. Consistent with its central role in coordinating inflammatory responses, numerous recent studies have implicated the transcription factor NF-κB in the development of such diseases, thereby further establishing inflammation as a critical factor in their etiology and offering hope for the development of new therapeutic approaches for their treatment.

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Serum Calcium Levels In Type 2 Diabetes Mellitus

By | Diabetes

Serum Calcium Levels In Type 2 Diabetes Mellitus

Kanchana. N, Saikumar. P

Hyperglycemia in Diabetes Mellitus is known to have its effect on almost all body system through alterations in structural and biochemical changes in tissues.From this study it is hypothesized that alteration in calcium flux may adversely affect the insulin secretion as it is a calcium dependent process.

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