Calcium, Magnesium, and Colorectal Cancer
Qi Dai, Robert S. Sandler, Elizabeth L. Barry, Robert W. Summers, Maria V. Grau, and
John A. Baron
High calcium consumption may confer a reduced risk of colorectal cancer.1,2 Dai and colleagues recently reported in a case-control study that intake of calcium may be associated with a decreased risk of colorectal adenoma only when the dietary calcium:magnesium intake ratio is low. This finding provides one possible interpretation for inconsistencies in previous studies of the association of calcium intake with risk of colorectal neoplasia.